Best genome Best GRN Best metabolic network Best phenotype Best local environment

Best genome Top


Best genetic regulation network Top


The graph is interactive: you can click and drag in the white area to move. You can scroll to zoom in or out. You can click and drag a node to move it. Groups of nodes, such as 'Transcription factors' or 'Co-enzymes', can also be moved together.
  • Green triangles represent co-enzyme metabolites (CoE). The metabolite tag is indicated under brackets,
  • Orange rectangles represent transcription factors (TF). They belong to 4 types: A Tfs are activated by their co-enzyme ; R TFs are inactivated by their co-enzyme ; AA TFs are always active ; AI TFs are always inactive. Transcription factors can be expressed by the genome (NI) or inherited from the mother's cytoplasm (I),
  • Blue circles represent enzymes (E). The metabolic reaction performed by the enzyme is indicated under brackets. "-" symbolizes an external metabolite (i.e., the enzyme is a pump).
Solid edges reprenset activation or upregulation. Dashed edges represent inhibition or downregulation.

Best metabolic network Top


The graph is interactive: you can click and drag in the white area to move. You can scroll to zoom in or out. You can click and drag a node to move it. Groups of nodes, such as 'Cell', can also be moved together.
  • Blue circles represent non essential metabolites. They are part of the metabolic network, but do not contribute directly to the fitness,
  • Green rectangles represent essential metabolites. They directly contribute to the fitness.
  • Negative nodes represent metabolites outside of the cell. In this case, they are pump in or out depending on the direction of the reaction link.
Solid edges represent the direction of the metabolic reactions.

Best phenotype Top


Environment state Top


The bar chart is interactive: you can mouse over to highlight individual values. Labels flanked with '|' are essential metabolites. Other labels are non essential metabolites.
  • Blue bars represent local metabolic concentrations in the environment,
  • Red bars represent global metabolic concentrations in the environment.